Finally, central adiponectin has been shown to regulate behaviors like food intake (Suyama et al., 2016), locomotor activity (Miyatake et al., 2015) as well as cognition, anxiety and mood (Jeong et al., 2012; Zhang et al., 2017; Cao et al., 2018; Cezaretto et al., 2018; Nicolas et al., 2018; Platzer et al., 2018; Sun et al., 2018). Here, ADIPOQ is linked to Anxiety.