Considering that the acute and chronic inflammation of the gallbladder (cholecystitis) are known hallmarks of GSD pathophysiology28, we explored the expression levels of the TRAF3 protein in 9 gallbladder mucosa samples (4 cases and 5 controls) and mRNA in 25 gallbladder (12 cases and 13 controls) and 41 duodenal (22 cases and 19 controls, independent from the mRNA samples) samples. Here, TRAF3 is linked to disorder of glycogen metabolism.