Since we originally identified ABCG8 as a risk factor for GSD in a German population from Kiel10,11, we therefore examined ABCG8 rs11887534 and TRAF3 rs12882491 variants in an extended sample from the original POPGEN-Kiel population consisting in 1,938 individuals (1,027 cases and 911 controls)22, as well as in 4,154 individuals (882 cases and 3,272 controls) from the north-east side of Germany identified as SHIP-Greifswald23 (Table 1). Here, TRAF3 is linked to disorder of glycogen metabolism.