We then analyzed the data from the TCGA (https://cancergenome.nih.gov) and GTEx (https://gtexportal.org/home/) databases, and the results were documented in Fig. 1b: ASF1a was overexpressed in HCC (liver hepatocellular carcinoma, LIHC), PCa, GC, and BC tumor tissues compared with their non-tumorous counterparts. This evidence concerns the gene ASF1A and hepatocellular carcinoma.