PSMD10 and cirrhosis of liver: Previous studies revealed that Gankyrin was an oncogene in HCC6, to reconfirm this, we detected the expression level of Gankyrin in normal liver tissues (n = 12), liver cirrhosis tissues (n = 81), primary liver cancerous tissues (n = 82) and hepatocellular carcinoma with portal vein tumor thrombus (PVTT) tissues (n = 26) by using immunohistochemical assays, western blot and qRT-PCR (Figs. 1a, b, e).