HDAC7 and neoplasm: We found the volume and weight of xenografts in ZNF326 + shRNA-HDAC7 group markedly reduced compared to the ZNF326 group (ZNF326 vs ZNF326 + shRNA-HDAC7, volume: 1.180 + 0.141 vs 0.736 + 0.052, P < 0.05; weight: 0.763 + 0.060 vs 0.366 + 0.041, P < 0.05), indicating that ZNF326 promotes tumour growth, at least partially through HDAC7 (Fig. 8a-c).