Having previously demonstrated that silencing CDH11 suppresses the stem cell-like phenotype of TNBC cells in vitro, to determine the probable inhibitory effect of silencing CDH11 on tumor formation and growth in vivo, we generated tumor xenograft models derived from NOD/SCID mice (n = 5/group) inoculated with 2 × 106 WT or siCDH11 MDA-MB-231 or Hs578t cells subcutaneously in the hind-flank and observed for 27 days (Figure 6A). The gene discussed is CDH11; the disease is neoplasm.