HNF1B and breast cancer: Based on breast cancer big data analyses, we showed that CDH11 expression positively correlates with expression of WNT signalling components such as β-catenin, WNT2, and TCF2, and that tissues from TNBC patients show concurrent high expression of CDH11 and β-catenin proteins; thus, we demonstrate that CDH11 positively modulates β-catenin expression and activates the canonical WNT signalling pathway (Figure 2).