PPARA and Insulin resistance: An experiment with mice fed with a high fat diet and treated with 0.32% EGCG for 16 weeks found a reduction in body weight and insulin resistance and an increase in the mRNA levels of the nuclear respiratory factor (Nrf1), medium chain acyl coA decarboxylase (Mcad), UCP3 and peroxisome proliferator α (PPAR-α) related to lipid metabolism [49].