There are several regulators of breast cancer metabolism such as phosphatidylinositol-4,5-bisphosphate 3-kinase (PI3K), MYC, ER, breast cancer susceptibility gene 1 (BRCA1), and p53 [18,19,20,21,22,23,24,25,26,27,28,29]. The gene discussed is TP53; the disease is breast cancer.