The promoter SNPs rs117039649 (SNP285G>C) and rs2279744 (SNP309T>G) in intron 1 of the MDM2 gene (hereafter referred to as SNP285 and SNP309, respectively) were genotyped in an Austrian hospital-based case-control study of 406 breast cancer patients and 254 control subjects. Here, MDM2 is linked to breast cancer.