We analyzed the expression pattern of 28 ataxia risk genes and found that majority of them are highly expressed in PCs, while only a few of them, including elongation factor 2 (Eef2), ataxin-10 (Atxn10), nucleolar protein 56 (Nop56), are widely expressed in all cell types (Figure 4A). Here, ATXN10 is linked to cerebellar ataxia.