MDM4 and cancer: It is worth noting that while particular interest has focused on distinguishing MDM4-FL from MDM4-S in cancers, such as those of the breast (Lenos et al., 2012), this work from the Jochemsen group (Phillips et al., 2010) would predict that more precise discrimination between the 75-kDa and 76-kDa forms in cancer would be extremely pertinent.