For example, in the Solomon Islands, a lack of increase in seropositivity to Pgp3 in 1–9-year-olds correlated with low infection rates, despite the 26% prevalence of TF, contrasting to the steep increase in seropositivity with age observed amongst 1–9-year-olds in Kiribati where TF prevalence was 28% and infection prevalence was 24% [21,22]. This evidence concerns the gene TF and infection.