Tumour volume in the normal saline treated group was 1803.2 mm3 at 54 days after tumour inoculation, while tumour volumes in the 103.6 MBq and 240.5 MBq of 188Re-HSA microspheres treated groups were 381 and 267.4 mm3 (P = 0.001 and 0.004), respectively, demonstrating the high therapeutic efficacy of this modality. The gene discussed is ALB; the disease is neoplasm.