RNASE3 and infection: In the context of infection, eosinophils are associated with parasite infestations where they possess toxic effects to the pathogen through degranulation and release of different cationic proteins, such as major basic protein (MBP), eosinophil peroxidase (EPO), eosinophil cationic protein (ECP), and eosinophil-derived neurotoxin (EDN) (Hogan et al., 2008; Ravin and Loy, 2015).