Epidermal growth factor receptor (EGFR) belongs to the family of receptor tyrosine kinases and is known to be an important regulator of multiple cellular processes in cancer-related diseases, as well as in pain processing and chronic kidney disease (Wang and Kim, 2002; Linggi and Carpenter, 2006; Chen et al., 2017; Martin et al., 2017). This evidence concerns the gene EGFR and chronic kidney disease.