Demographic-based•    Born 1945––1965 tested once•    All pregnant women*Risk-based•    Ever injected drugs•    Received clotting factor concentrates before 1987•    Ever on long-term hemodialysis•    Persistently abnormal alanine aminotransferase (ALT) levels•    HIV infection•    Transfusion of blood or blood components or an organtransplant before July 1992•    Health-care, emergency medical, and public safety workersafter needle sticks, sharps, or mucosal exposures to hepatitisC virus (HCV)-positive blood•    Children born to HCV-positive women. The gene discussed is GPT; the disease is HIV infectious disease.