TRAF3 and B-cell neoplasm: In contrast, the B cell neoplasms developed by the B cell-specific Traf3-deficient mice (28) were consistent with SBL/CLL and MZL, with over 86% of the expanded cloned having non-mutated VHDJH regions (applying the 97.5% identity to the germ line criteria that we have used in our analyses).