Similarly, rs1801028, a SNP occurring in DRD2 gene and determining a Ser-to-Cys substitution at position 311 of DRD2 gene (Ser311Cys) has been shown to alter the physiology and function of DRD2 receptor (72) and has consistently been associated with risk for schizophrenia in a number of studies since 1994 (73)—for a meta-analysis see: (74). Here, DRD2 is linked to schizophrenia.