GSK3B and schizophrenia: For example, rs1130233, a cis-eQTL of AKT1 gene that interacts with rs1076560 in affecting pre-frontal AKT1 mRNA expression levels along with level of phosphorylation of the AKT1 kinase target GSK3beta, interacts with rs1076560 also on cingulate cortex activity during attentional control, another cognitive function typically impaired by schizophrenia (67).