It has been accepted that the Ki-67 PI value is 3.0 ± 2.1% in grade II gliomas, 11.8 ± 3.4% in grade III anaplastic gliomas and 15.8 ± 7.4% in grade IV GBMs (Johannessen and Torp, 2006). This evidence concerns the gene MKI67 and glioma.