We selected a fixed dose of adjuvant hCG 1000 IU at the time of GnRH agonist trigger for the study group (Group 1) based on the assumption that it may be high enough to rescue a few of the corpora lutea to optimize conception rates, but not too high to rescue excessive numbers of CL, thereby reducing the risk of significant OHSS development [13]. The gene discussed is GNRH1; the disease is ovarian hyperstimulation syndrome.