The MT-ND1 gene has been examined in association with several diseases including recurrent pregnancy loss [48], colorectal cancer [49], bladder cancer [47], Parkinson’s disease [50, 51], and contradicting results have been published regarding it’s possible effect on multiple sclerosis [52] and Leber’s optic atrophy [53–55]. This evidence concerns the gene MT-ND1 and Leber hereditary optic neuropathy.