Of interest were those cases in which multiple SVs involving PD-L1 and/or PD-L2 were observed in a single tumor (DLBCL58, MCL29, and ANKL7), underscoring the importance of the deregulated expression of these PD-1 ligands in clonal selection and expansion of these tumors. This evidence concerns the gene PDCD1LG2 and neoplasm.