ATXN2L and epilepsy: This is surprising because α2δ subunits are strongly expressed in GABAergic neurons (Cole et al., 2005; Schlick et al., 2010) and aberrant GABAergic signaling is primarily implicated in the etiology of the abovementioned neurological disorders (e.g., epilepsy; Bonansco and Fuenzalida, 2016).