Orange dots represent cell lines that are the most dependent on SLC25A22, but not dependent on SLC25A18. Conversely, the red dot represents a cell line (oral squamous cell carcinoma HSC-3) that is dependent on SLC25A18, but not dependent on SLC25A22. On the middle panel of Fig. 7h, we show LFCs for guides A4 and B4. This evidence concerns the gene SLC25A22 and oral cavity squamous cell carcinoma.