It was found that conditioned medium from SDCSC exosome-trained neutrophils suppressed the proliferation of activated T cells (Additional file 9: Figure S7A, right panel) and attenuated the expression of Il2, a key cytokine for T cell proliferation [44], and Ifnr, a mediator of T cell-dependent anti-tumor responses [45], in activated T cells (Additional file 9: Figure S7B). The gene discussed is IFNAR2; the disease is neoplasm.