In addition to this report, other tumor-related genes, including hTERT [43], c-kit [44], KRAS [45,46], BCL2 [47], and VEGF [48], were identified as genes in which the formation of a G4 was involved in transcriptional regulation, and its stabilization by small molecules attenuated promoter activity, eventually inducing tumor apoptosis. This evidence concerns the gene BCL2 and neoplasm.