VEGFA and non-small cell lung carcinoma: In order to better understand the mechanism by which VEGFq inhibits proliferation of NSCLC cells, we investigated its effect on run-on transcription of VEGF. VEGFq treatment of A549 cells decreased newly synthesized VEGF mRNA by 40% after 72h compared to untreated and cells treated with MutVEGF (Fig 8A).