An SDHB‐negative gastrointestinal stromal tumor (GIST) from a patient with a heretozygous germline SDHA 3‐base deletion that spans the IVS4/exon 5 junction (c.457‐2_c457delAGC) (Belinsky, et al., 2013) and two RCC tumors with clear cell features from a patient with wild‐type SDHA and SDHB were used as controls. The gene discussed is SDHA; the disease is gastrointestinal stromal tumor.