AF patients had significantly higher levels of total cMPs (P < 0.001), PMPs (P = 0.002), EMPs (CD31+ CD41−) (P < 0.001), red blood cell‐derived microparticle (RMPs) (P = 0.020), and tissue factor bearing microparticle (TF‐MPs) (P = 0.014) than healthy controls. The gene discussed is TF; the disease is atrial fibrillation.