IKBKB and neoplasm: The contradictory results observed in two different studies with similar model could be explained as (1) IKKβ was deleted in type-I-collagen fibroblast by the first research group and in type-VI-collagen fibroblast by the latter one; (2) besides genetic background of the mice, timing of IKKβ deletion and (3) existence of heterogeneous fibroblast subpopulation in tumor stroma might play a role in different findings (Wagner 2016).