The recruitment of TAN is achieved through the release of specific chemokines from the tumor microenvironment—CXCL1, CXCL2; cytokines—INF- γ, TNF-α; growth factors—granulocyte colony stimulating factor (G-CSF) and presence of specific adhesion molecules on the EC surface [47, 49]. The gene discussed is CSF3; the disease is neoplasm.