Moreover, as FasL is implicated in GBM growth and invasion through the induction of apoptosis in infiltrating lymphocytes, which facilitate the evasion of the immune system by the tumor [17] we evaluated FasL expression by Western Blot analysis, observing a significant increase of FasL expression in human GBM samples respect to control samples (Figure 10E). This evidence concerns the gene FASLG and glioblastoma.