To further study the association between Linc00441 expression and gastric cancer, we tested Linc00441 expression in various human gastric cancer cell lines and found that Linc00441 was up-regulated in HGC-27 and AGS cells and down-regulated in SGC-7901 and KATO III cells compared with MGC-803 and NCI-N87 cells (Figure 3A). The gene discussed is RB1-DT; the disease is gastric cancer.