Within LPS-treated groups, time since LPS injection influenced hippocampal (F1,87 = 37.8, p < 0.001) and frontal cortex Il-1β (F1,87 = 60.1, p < 0.0001; Fig. 6A–C), such that Il-1β levels receded over time after LPS injection for all tumor treatments. Here, IL1B is linked to neoplasm.