In this study, we selected six SNPs in the DUT gene with minor allele frequency values greater than 0.05, and explored their distribution frequency in a case-control study (400 cervical squamous cell carcinomas (CSCCs), 400 precursor cervical intraepithelial neoplasia (CIN) III lesions and 1,200 normal controls). This evidence concerns the gene DUT and uterine cervix carcinoma in situ.