RCC (n = 10) and NSCLC (n = 2) had limited number of patients treated with anti-CTLA4 agents, but RNA-seq high was associated with the only RCC response to ipilimumab + nivolumab, as well as non-response for all RNA-seq low patients (Additional file 1: Table S5). The gene discussed is CTLA4; the disease is non-small cell lung carcinoma.