Phosphorylated FoxO1 and Atg7 are located in autophagosomes, suggesting that the association of cytosolic phosphorylated FoxO1 with Atg7 likely contributes to the autophagy induction of iNKT cells indicated by MAP1LC3β/LC3β lipidation and sequestosome 1(SQSTM1/p62) degradation, initiating NKT cells development and effector functions against viral infection [84]. The gene discussed is SQSTM1; the disease is viral infectious disease.