EGFR and non-small cell lung carcinoma: For example, it was reported that erlotinib (a standard therapy in EGFR-mutant lung cancer) induced autophagy in growth factor receptor mutated non-small cell lung cancer (NSCLC) cells, which caused drug resistance, but inhibition of autophagy by chloroquine (CQ) can enhance the pro-apoptotic effects of erlotinib [43].