In particular, the described concurrence of HSPA8 and RyR2 for atrial fibrillation and myocardial infarction, the involvement of DUSP4 in I/R injury, the role of PHLPP2 in developing complications after cardiac surgery and the involvement of BBS9 in renal dysfunction could be interesting for further future examinations. This evidence concerns the gene RYR2 and atrial fibrillation.