Indeed, multiple Hypoxia-inducible factor 1alpha (HIF-1α)-induced miRNAs, called hypoxia-regulated microRNAs (HRMs), have been shown to modulate post-stroke angiogenesis by targeting the vascular endothelial growth factor A (VEGF-A) pathway [17,18,19,20,21]. The gene discussed is HIF1A; the disease is Stroke.