DNM2 and chronic myelogenous leukemia, BCR-ABL1 positive: Here, the identified AHI-1-BCR-ABL-DNM2 complex was shown to regulate endocytosis and ROS generation, both of which lead to autophagy induction in CML, but knockdown of DNM2 disrupted these activities and reduced autophagy induction in primitive leukemic cells [75].