In line with these observations, Watson et al. also demonstrated that human AML blasts exhibit low expression of several autophagy genes, including ATG10, ATG5, ATG7, BECN1, GABARAP, GABARAPL1/2, and MAP1LC3B, decreased autophagic flux, and high ROS levels [42]. The gene discussed is ATG5; the disease is acute myeloid leukemia.