FN1 and cancer: We here studied in more details the molecular mechanisms underlying the role of KV11.1 in cancer cell motility, using PDAC cells as a model, in two experimental conditions: cells adhering and migrating onto a single ECM protein, FN, and cells cultured on a desmoplastic, collagen-rich matrix, with the addition of a conditioned medium produced by pancreatic stellate cells cultured in hypoxia (DM plus Hypo-PSC-CM), which better mimics the PDAC microenvironment.