We further elaborate the mechanism of this neuroprotective effect of ST extract against MPTP-induced Parkinsonism by assaying the activities of the dopaminergic system (the levels of dopamine (DA), its metabolites (3,4-dihydroxyphenylacetic acid (DOPAC) and homovanillic acid (HVA)), and the expression of tyrosine hydroxylase (TH)) and antioxidant defense, GSK3-β phosphorylation, and α-synuclein levels in the mouse striatum. This evidence concerns the gene TH and Parkinson disease.