In 2013, we reported that the most frequent Polish path_BRCA1 variant had the same lower incidence for breast cancer as the Norwegian frequent path_BRCA1 variants, while the North-American less frequent path_BRCA1 variants implied higher risk for infiltrating breast cancer, similar to the less frequent Norwegian path_BRCA1 variants [5]. The gene discussed is BRCA1; the disease is breast carcinoma.