In AML patients with the t(15;17) translocation, SSX2IP levels were associated with gene expression of proteins involved in regulating cyclin dependent kinases (CDK) activity (p57Kip2, cdk7, cyclins D2, D3, E2, and B2), DNA replication (CDC6) and mitosis (survivin and CENPJ) [73]. The gene discussed is BIRC5; the disease is acute myeloid leukemia.