Xue et al. showed that T cells isolated from CML and AML patients and transduced with a WT1-TCR gene are able to eliminate leukemic cells in an HLA-A2-restricted manner in the non-obese diabetic–severe combined immunodeficiency (NOD/SCID) murine model [54]. This evidence concerns the gene WT1 and chronic myelogenous leukemia, BCR-ABL1 positive.