To analyze global changes in cellular proteins accompanying HCMV latent infection of CD14+ monocytes, we initially enriched for the latent HCMV population by infecting monocytes with a clinical isolate of HCMV, TB40E, which expresses GFP from an SV40-GFP expression cassette, and isolated latently infected GFP-positive cells 72 h following infection (Lau et al., 2016a). Here, CD14 is linked to disease arising from reactivation of latent virus.