Recent studies demonstrated that Gal‐9 induced various biological reactions, such as cell aggregation, adhesion, activation, and apoptosis.36, 37 Gal‐9 showed immunomodulatory properties by inducing Th1 cell (not Th2 cell) death through interaction with Tim‐3.38 In addition, Tim‐3 and Gal‐9 were also expressed in brain tissues and involved in inflammation in the rat stroke model.21 High‐level expression of Tim‐3 in glial cells triggers and activates the Tim‐3/Gal‐9 signaling pathway and promotes the release of pro‐inflammatory factors, but its role in ICH is unknown. This evidence concerns the gene HAVCR2 and Stroke.