H19 and Marfan syndrome: Increased levels of H19 are associated with increased risk of coronary artery disease in patients.44 In addition, H19 was induced in heart failure patients.45H19 in association with miR‐675 axis was shown to regulate cardiomyocyte apoptosis and diabetic cardiomyopathy.46, 47 The same axis (H19‐miR‐675) is reported to function as a negative regulator of cardiomyocyte hypertrophy in mice.48 However, the role of H19 in context of MFS is unclear and we believe it could be an interesting target to investigate.