The eukaryotic translation initiation factor 4E is a key regulator of protein synthesis, which is generally the rate‐limiting factor recruits mRNAs to eIF4F.30 Uncontrolled of eIF4E activity or expression in various cancers stimulates cellular proliferation and malignant transformation.39, 40 Thus, eIF4E has been considered as a therapeutic target in cancer. The gene discussed is EIF4E; the disease is cancer.