We found a significant expansion (~2.5-fold) of effector memory CD8+ T cells and antigen-experienced (CD11ahigh) CD8+ T cells (~6-fold), and a concomitant reduction (~2.5-fold) in central memory CD8+ T cells in the ZIKV-infected compared with mock-infected mice on day 10 post-infection (S9A & S9B Fig). This evidence concerns the gene CD8A and infection.